CAPIFLO

Capecitabine Tablets IP 500mg

DESCRIPTION

As a prodrug, Capecitabine is selectively activated by tumor
cells to its cytotoxic moiety, 5-fluorouracil (5-FU). 5-FU is
metabolized to two active metabolites, 5-fluoro-2-
deoxyuridine monophosphate (FdUMP) and 5-fluorouridine
triphosphate (FUTP) by both tumor cells and normal cells.
FdUMP inhibits DNA synthesis and cell division by reducing
normal thymidine production, while FUTP inhibits RNA and
protein synthesis by competing with uridine triphosphate for
incorporation into the RNA strand.

Description

CAPIFLO is used to treat Adjuvant Colon Cancer, Metastatic Colorectal Cancer, and Metastatic Breast Cancer. How does it work Capecitabine is metabolized to 5-FU which in turn is a thymidylate synthase inhibitor, hence inhibiting the synthesis of thymidine monophosphate (TMP), the active form of thymidine which is required for the synthesis of DNA.

Reviews

There are no reviews yet.

Be the first to review “CAPIFLO”

Your email address will not be published. Required fields are marked *