Oxaliplatin Injection IP 50mg/100mg


Oxaliplatin binds preferentially to the guanine and cytosine
moieties of DNA, leading to cross-linking of DNA, thus
inhibiting DNA synthesis and transcription. Cytotoxicity is cellcycle nonspecific.


FLOPLATIN USE TO TREAT Inhibition of Topoisomerase 2High affinity binding to DNA  through intercalation Binding top cell membrane and affect the fluidity of the membrane generation of free radicalsoxaliplatin forms both inter-and intra-strand cross-links in DNA, which prevent DNA replication and transcription, causing cell death.


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